PhospoPep is a project to support systems biology signaling research in D. melanogaster. So far it contains phosphorylation site data of D. melanogaster Kc167 cells generated by the Aebersold group at the Swiss Federal Institute of Technology (ETH) in collaboration with the Functional Genomics Center ( FGCZ ) in Zurich, Switzerland, and the Institute for Systems Biology (ISB) in Seattle, Washington USA.

At the moment PhosphoPep contains over 10,000 high quality phosphorylation sites mapping to nearly 4,600 phosphoproteins (3,500 gene models) of D. melanogaster Kc167 cells and thus being the most comprehensive phosphorylation map in any system to date. Furthermore, PhosphoPep offers different software tools which allow users to browse through single proteins, through pathways, and importantly to integrate the data with information from external sources, like protein-protein interaction data. Finally all data can be readily exported e.g. for a targeted proteomics approach and the generated data can be again validated using PhosphoPep, enabling systems biology signaling research.